RCT2021 · Science · Yoshino M et al.
NMN improves muscle insulin sensitivity in prediabetic women
Who, how long
25 postmenopausal, prediabetic, overweight women, 10 weeks
What they found
250 mg/day NMN improved insulin-stimulated glucose uptake in muscle by 25% — the first placebo-controlled human NMN data.
⚠ Caveat
Very small sample; body weight, lipids and blood pressure unchanged; the effect size is clinically modest.
Related in the knowledge base
Last reviewed: 6 September 2026
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