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Longevity Atlas
Heart, metabolismµIU/ml

Fasting insulin / HOMA-IR

Optimal

Insulin < 8 µIU/ml; HOMA-IR < 1.5

Why

Insulin resistance precedes diabetes by 10–15 years; fasting glucose is still normal while insulin is already elevated.

How often

Yearly after 40 or with abdominal obesity.

What moves it

Same as HbA1c — exercise is the fastest lever.

Last reviewed: 6 September 2026

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