Cohort2018 · AJCN · Kiechl S et al.
Spermidine intake and mortality in the Bruneck cohort
Who, how long
829 South Tyrolean adults (45–84), 20 years
What they found
The highest-intake third had mortality as low as if they were 5.7 years younger.
⚠ Caveat
Food-frequency questionnaire; spermidine-rich foods (whole grains, legumes, cheese) also mark a healthy diet. The SmartAge RCT (2022) found no memory benefit from supplements.
Related in the knowledge base
Last reviewed: 6 September 2026
This site is educational and does not replace medical advice. Start any supplement or drug only after consulting a doctor or pharmacist.