TargetedHeart, metabolismVegan form available
Coenzyme Q10 (ubiquinol)
Reduced mortality in heart failure in the Q-SYMBIO RCT; mixed data for statin muscle pain.
3/5· Multiple human trialsEstimated monthly cost: ≈ 15 €
Dose
100–200 mg ubiquinol; 300 mg in heart failure with a doctor.
Timing
With a fatty meal.
⚠ Cautions
May reduce warfarin's effect.
What it is
A member of the mitochondrial electron transport chain; synthesis falls with age and on statins.
What the evidence shows
Q-SYMBIO (n=420, 2 years, 300 mg): 43% fewer major cardiovascular events in heart failure. For statin myalgia, meta-analysis shows a small improvement.
Goals
Heart, blood sugarEnergy, fatigue
Sources
Last reviewed: 6 September 2026
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